High blood calcium
Clinically: Hypercalcaemia
· also high calcium, raised calcium, hypercalcemia disease
unverified These explanations are written to be easy to read and have not yet been checked against a source. The ranges and measurement notes on this page show theirs.
definition unverified
Calcium in the blood is above normal. The two usual explanations are an overactive parathyroid gland or, less often, an underlying malignancy.
Serum calcium concentration above the normal range, defined as greater than 10.5 mg/dL and graded mild (10.5-12 mg/dL), moderate (12.1-14 mg/dL) or severe (above 14 mg/dL). Most cases are caused by primary hyperparathyroidism, with excess PTH secretion from enlarged or adenomatous parathyroid glands, or by malignancy.
caveats unverified
The typical lab pattern
The results a diagnosis is actually made on.
| Calcium, total | high | — | Defined as serum calcium above 10.5 mg/dL: mild 10.5-12, moderate 12.1-14, severe above 14 mg/dL. |
Fits the picture, but not enough on its own.
| Albumin | either | — | Total calcium should be corrected for albumin, the main protein that carries calcium in the blood. |
| Phosphate | low | — | Low phosphate with high calcium points towards too much parathyroid hormone, which makes the kidneys lose phosphate. |
| Alkaline phosphatase | high | — | Often raised in primary hyperparathyroidism, the most common cause, and falls after surgery. |
How it usually feels
- Deep aching in the bones · occasional
- Difficulty passing stool · occasional
- Feeling tired all the time · common
- Trouble thinking clearly · occasional
- Urinating much more than usual · occasional
Frequencies say how often a symptom accompanies this condition — not the other way round. Most people with any of these symptoms do not have this.