Underactive thyroid
Clinically: Hypothyroidism
· also underactive thyroid, low thyroid, slow thyroid, Hashimoto
unverified These explanations are written to be easy to read and have not yet been checked against a source. The ranges and measurement notes on this page show theirs.
definition unverified
Your thyroid is not making enough hormone. Your whole body then runs slower than it should. That includes your heart rate, your digestion, and your thinking.
Production by the thyroid gland of too little thyroid hormone to meet the body's needs, most commonly due to Hashimoto's disease, an autoimmune thyroiditis. In primary disease the pituitary keeps releasing TSH, so serum TSH is high; a low T4 also indicates hypothyroidism.
why measured unverified
The symptoms are vague and easy to attribute to stress or ageing, but the blood test is simple and the treatment is usually straightforward.
The symptoms are vague and easy to attribute to stress or ageing, but the blood test is simple and the treatment is usually straightforward.
No clinical version written yet.
caveats unverified
The test result runs in the opposite direction to intuition. A HIGH TSH means an UNDERactive thyroid, because TSH is the signal your brain sends telling the gland to work harder. A short illness can shift the number temporarily, so an odd result is usually repeated once you are well.
The test result runs in the opposite direction to intuition. A HIGH TSH means an UNDERactive thyroid, because TSH is the signal your brain sends telling the gland to work harder. A short illness can shift the number temporarily, so an odd result is usually repeated once you are well.
No clinical version written yet.
Common, and several times more so in women. The likelihood rises steadily with age. Autoimmune thyroiditis is the usual cause where iodine intake is adequate.
The typical lab pattern
The results a diagnosis is actually made on.
| Thyrotropin | high | — | TSH above the reference range is part of the definition, and is usually the first test checked. |
| Thyroxine, free | low | — | Primary hypothyroidism: TSH above and free T4 below the reference range. A high TSH with normal free T4 is the milder, subclinical form. |
Fits the picture, but not enough on its own.
| Triiodothyronine, free | low | — | Low T3 can mean hypothyroidism, but T3 is rarely used to diagnose it because TSH and free T4 pick it up earlier. |
| Cholesterol, total | high | ref ≤ 200 | Hypothyroidism raises total and LDL cholesterol; people with high cholesterol are advised to be tested for it. |
How it usually feels
- Difficulty passing stool · occasional
- Dry, rough skin · common
- Feeling cold when others do not · common
- Feeling low or flat · occasional
- Feeling tired all the time · common
- Gaining weight without eating more · common
- Hair thinning or falling out · occasional
- Trouble thinking clearly · common
Frequencies say how often a symptom accompanies this condition — not the other way round. Most people with any of these symptoms do not have this.